Cleveland is a city in the state of Ohio and is the county seat of Cuyahoga County, the most populous county in the state. The city is located in northeastern Ohio on the southern shore of Lake Erie, approximately 60 miles (97 km) west of the Pennsylvania border. It was founded in 1796 near the mouth of the Cuyahoga River, and became a manufacturing center owing to its location on the lake shore, as well as being connected to numerous canals and railroad lines. Cleveland's economy has diversified sectors that include manufacturing, financial services, healthcare, and biomedical. Cleveland is home to the Rock and Roll Hall of Fame.As of the 2013 Census Estimate, the city proper had a total population of 390,113, making Cleveland the 48th largest city in the United States, and the second largest city in Ohio after Columbus. Greater Cleveland, the Cleveland-Elyria-Mentor, OH Metropolitan Statistical Area, ranked 29th largest in the United States with 2,064,725 people in 2013. Cleveland is part of the larger Cleveland-Akron-Canton, OH Combined Statistical Area, which in 2013 had a population of 3,501,538, and ranked as the country's 15th largest CSA.