Nashville is the capital of the U.S. state of Tennessee and the county seat of Davidson County. It is located on the Cumberland River in the north-central part of the state. The city is a center for the music, healthcare, publishing, banking and transportation industries, and is home to a large number of colleges and universities. Reflecting the city's position in state government, Nashville is home to the Tennessee Supreme Court's courthouse for Middle Tennessee. It is known as a center of the music industry, earning it the nickname "Music City".Nashville has a consolidated city–county government which includes six smaller municipalities in a two-tier system. As of the 2010 census the population of Nashville, not including the semi-independent municipalities, stood at 601,222. The population of Nashville as a whole, including all municipalities, was 626,681. Nashville is the second largest city in Tennessee, after Memphis, and the fifth largest city in the Southeastern United States. The 2010 population of the entire 13-county Nashville metropolitan area was 1,589,934, making it the largest Metropolitan Statistical Area in the state. The 2010 population of the Nashville-Davidson–Murfreesboro–Columbia combined statistical area, a larger trade area, was 1,670,890.