Gross Lab - University of Pittsburgh School of Medicine

at University of Pittsburgh School of Medicine, Pittsburgh , 15213 United States

1. School
2. Education

Welcome to the Gross Lab at the University of Pittsburgh School of Medicine. We use zebrafish to study eye development and diseases of the eye.

Description

Our research focuses on vertebrate eye development utilizing the zebrafish as a model system. Combining forward genetic screens with reverse genetic and embryological manipulations we hope to understand the molecular, cellular and developmental events that regulate eye formation and visual function. Current areas of interest in the lab include studies focusing on the development and maintenance of the lens, retina, hyaloid vasculature and retinal pigmented epithelium of the eye, and elucidation of the molecular and cellular mechanisms that regulate ocular morphogenesis. Our research combines molecular, cellular, biochemical, transgenic and in vivo imaging techniques to address these questions. It is our hope that these studies will ultimately lead to a better understanding of visual system disorders such as macular degeneration, cataracts and ocular colobomas that often result in blindness in afflicted patients. Finally, we also have an interest in evolution of the eye and have recently initiated studies of eye development in squid to address this topic.

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Summary

Gross Lab - University of Pittsburgh School of Medicine is Pittsburgh based place and this enity listed in School category. Located at University of Pittsburgh School of Medicine PA 15213.